Genomic analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains isolated in Malaysia

Authors

  • Hooi-Leng Ser
  • Loh Teng-Hern Tan
  • Jodi Woan-Fei Law
  • Vengadesh Letchumanan
  • Nurul-Syakima Ab Mutalib
  • Learn-Han Lee

DOI:

https://doi.org/10.36877/pmmb.a0000093

Abstract

Using seven complete genomes of human SARS-CoV-2 (retrieved from GISAID) isolated in Malaysia for
phylogenetic tree construction, the current study showed that these strains formed four distinct clades when compared with other representative strains from Asia, Europe and US. In light of that, the genome sequences of these strains isolated in Malaysia suggested that there is currently more than one “type” of strain within the country. Complementing with epidemiological and experimental studies, these findings allow better understanding the prevalence of certain types in Malaysia and permits further in-depth studies on the virulence and pathogenic mechanisms of these strains which is particularly critical to speed up the development of effective treatment regime.

Downloads

Additional Files

Published

2020-06-18

How to Cite

Ser, H.-L., Tan, L. T.-H., Law, J. W.-F., Letchumanan, V., Ab Mutalib, N.-S., & Lee, L.-H. (2020). Genomic analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains isolated in Malaysia. Progress In Microbes & Molecular Biology, 3(1). https://doi.org/10.36877/pmmb.a0000093

Issue

Vol. 3 No. 1 (2020)

Section

Original Research Articles

License

Copyright (c) 2020 Hooi-Leng Ser, Loh Teng-Hern Tan, Jodi Woan-Fei Law, Vengadesh Letchumanan, Nurul-Syakima Ab Mutalib, Learn-Han Lee

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Author(s) shall retain the copyright of their work and grant the Journal/Publisher right for the first publication with the work simultaneously licensed under:

Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). This license allows for the copying, distribution and transmission of the work, provided the correct attribution of the original creator is stated. Adaptation and remixing are also permitted.

 

This broad license intends to facilitate free access to, as well as the unrestricted reuse of, original works of all types for non-commercial purposes.

The author(s) permits HH Publisher to publish this article that has not been submitted elsewhere.

Abstract viewed = 729 times
PDF downloaded = 490 times Supplementary downloaded = 0 times